PNC-27
PNC-27 is a synthetic peptide incorporating the MDM2-binding domain of p53, studied for its ability to selectively form membrane pores in cancer cells expressing membrane-bound MDM2.
Research Applications
- p53-MDM2 interaction and cancer cell membrane research
- Selective cytotoxicity mechanism studies in vitro
- Cell membrane pore-formation research models
Compound Information
Synthetic peptide incorporating the p53 MDM2-binding domain conjugated to a membrane-penetrating sequence. Supplied as lyophilised powder.
Technical Specifications
- Molecular Weight: ~4031.7 g/mol
- Sequence: Pro-Pro-Leu-Ser-Gln-Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu
Formula/weight figures for PNC-27 vary between suppliers; the figure above reflects the most consistent source found.
For laboratory research use only. Not for human or veterinary use. Not a drug, food, cosmetic, or dietary supplement, and not evaluated by the MHRA or any regulatory body for safety or efficacy. Buyers are responsible for ensuring their use complies with applicable laws and regulations.